欢迎来到 haemtech中国区代理商/公司/官网
全国咨询热线: 15172431432
联系我们

地址:武汉市洪山区光谷大道35号光谷总部国际时代 二期1栋1301

电话:13212737804

传真:18771149750

邮箱:sales@amyjet.com

新闻中心
logo.pngexocell.jpg

<

艾美捷科技代理Gene Tools品牌


Gene Tools是一家生产和销售Morpholino Anti-sense oligos(反义寡核苷酸)的公司,其产品专门用于基因调控的科学研究和药物开发。Gene Tools公司由多位资深科学家组成,为全球客户提供免费的技术咨询和Morpholino 序列设计服务。 Morpholino作为基因调控研究的最佳工具,已被广泛用于:阻断靶mRNA 翻译 (下调基因);诱导RNA选择性剪接 (下调或上调基因);阻断 miRNA;阻断病毒 RNA;阻断 non-coding RNA。


Morpholino介绍

Morpholino属于第三代反义寡核苷酸,主要通过阻断蛋白质翻译过程而达到抑制目标基因功能的作用,目前已经广泛用于发育生物学和细胞学实验中,并取得了非常好的实验效果。

Morpholino以吗啉环类似物为基本骨架,这种独特的结构特性使得Morpholino 具有以下几个特点:

● 与其他类型的反义寡核苷酸相比,Morpholino 能更好地抵抗核酸酶的作用;

● Morpholino 与靶序列结合后通过空间位阻效应发挥作用, 不激活RNaseH,不引起目标基因mRNA 的降解 ;

● 针对翻译起始位点区设计的Morpholino 用于抑制蛋白质的翻译,针对 pre-mRNA 剪切位点区设计的Morpholino 可影响mRNA 剪切,得到不 同的转录本,可以方便地用于目标基因结构域的突变研究;

● 与靶序列结合能力强,可以渗入mRNA 的二级结构, 并且特异性好。

配合Morpholino 的使用,Gene Tools公司开发了相应的递送系统,可以安全、高效地将Morpholino 输送至胞内,因此,Morpholino 也可以用于遗传学研究和新药靶标的发现以及验证。此外,Morpholino 可以标上荧光基团、亲和标签以及活性反应基团,以供不同的研究需要。

Gene Tools代理.png


Gene Tools公司产品介绍

● Custom Morpholino:可以根据目标基因序列定制设计并合成Morpholino,用于体外细胞实验或某些直接显微注射的模型(如斑马鱼、非洲爪蟾胚胎)。

● Vivo-Morpholino:适用于活体动物模型(小鼠,大鼠,狗,灵长类等),细胞培养,器官培养等。通过特殊的末端修饰,提高了其穿透细胞膜进入组织细胞的能力,使得在成年动物(主要是小鼠、大鼠)中进行系统性基因功能研究成为可能。

● Prepared Control Oligos:根据特定需求合成细胞穿透肽偶联的 Morpholino。适用于活体动物模型(小鼠,大鼠,狗,灵长类等),细胞培养,器官培养等。


产品名称Short DescriptionOligo sequenceSKU
Standard Control Oligo Negative control oligoCCTCTTACCTCAGTTACAATTTATAPCO-StandardControl-100
Vivo-Morpholino Standard Control OligoNegative Vivo-Morpholino control oligoCCTCTTACCTCAGTTACAATTTATAPCO-VivoStandardControl-100
Random Control Oligo 25-N25-base random sequence mixtureNNNNNNNNNNNNNNNNNNNNNNNNNPCO-RandomControl-25N-100
Zebrafish p53 oligoDanio rerio apoptosis suppression oligoGCGCCATTGCTTTGCAAGAATTGPCO-ZebrafishP53-100
Zebrafish Chordin Positive Control OligoDanio rerio Chordin positive control oligoATCCACAGCAGCCCCTCCATCATCCPCO-ZebrafishChordin-100-F
Clawed Frog Beta Catenin Positive Control OligoXenopus laevis Beta Catenin antisense oligoTTTCAACCGTTTCCAAAGAACCAGGPCO-BetaCatenin-100-F
Green Fluorescent Protein Positive ControlTranslation blocker for GFP targetACAGCTCCTCGCCCTTGCTCACCATPCO-GFPControl-100
Vivo-Morpholino GFP Positive ControlTranslation blocker for GFP target (Vivo-Morpholino)ACAGCTCCTCGCCCTTGCTCACCATPCO-VivoGFPControl-100
Fluoresceinated Vivo-Morpholino Std ControlNegative Vivo-Morpholino control oligo with 5'FluoresceinCCTCTTACCTCAGTTACAATTTATAPCO-FluorVivoStandardControl-100-F


● Endo-Porter:为了解决Morpholino在体外培养细胞中摄取效率低的问题,Gene Tools 开发了 Endo-Porter 这种特殊的转染试剂。它通过温和的内吞体逃逸机制帮助Morpholino进入细胞质。



" data-original="http://haemtech.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="艾美捷科技代理Gene Tools品牌全系列产品">
艾美捷科技代理Gene Tools品牌全系列产品
...
阅读详情
invivoCrown IV0106替换BioXCell BE0090 invivoCrown IV0106替换BioXCell BE0090
InVivoPro Rat IgG2b in vivo Isotype control ...
阅读详情
invivoCrown IV0106替换BioXCell BE0090 invivoCrown IV0106替换BioXCell BE0090
InVivoPro Rat IgG2b in vivo Isotype control ...
阅读详情
invivoCrown IV0120替换BioXCell BE0015-1 invivoCrown IV0120替换BioXCell BE0015-1
InVivoPro Anti-Mouse CD28 in vivo antibody, Clone 37.51 ...
阅读详情
invivoCrown IV0105替换BioXCell BE0089 invivoCrown IV0105替换BioXCell BE0089
InVivoPro Rat IgG2a in vivo Isotype control ...
阅读详情
invivoCrown IV0104替换BioXCell BE0061 invivoCrown IV0104替换BioXCell BE0061
InVivoPro Anti-Mouse CD8α in vivo antibody, Clone 2.43 ...
阅读详情
invivoCrown IV0107替换BioXCell BE0273 invivoCrown IV0107替换BioXCell BE0273
InVivoPro Anti-Mouse PD-1(CD279) in vivo antibody, Clone 29F.1A12 ...
阅读详情
42 life science 2.5比1.png

<

艾美捷科技代理42 life sciences品牌全系列产品


42 life sciences是一家位于德国北部不来梅港的中小型企业。42 life sciences专注于开发和生产用于免疫组化(IHC)及原位杂交(ISH)应用的创新试剂。公司的核心优势在于拥有经验丰富的生物技术专家团队,确保产品开发高效聚焦,同时以可靠且具成本效益的方式进行生产。所有研发与制造流程均在我们自有设施中严格遵循EN ISO9001和EN ISO 13485标准执行。

42 life sciences公司的产品与服务包括:免疫组化与原位杂交创新试剂;外包生物缓冲液及试剂的生产业务。


42lifesciences页面.png


▎42 life sciences产品列表

分类品名产品描述货号规格
Chromogens for HRPAEC Solution IHC (ready-to-use)AEC (3-Amino-9-Ethylcarbazole) is a commonly used chromogen for immunohistochemical (IHC) procedures supplied in one liquid component.S-99012-100;S-99012-1000100ml;1000ml
Chromogens for HRPAEC Solution ISH (ready-to-use)AEC (3-Amino-9-Ethylcarbazole) is a commonly used chromogen for chromogenic in situ hybridization (CISH) procedures supplied in one liquid component.S-99010-500;S-99010-1000500ml;1000ml
Chromogens for HRPDAB Solution Set (2 components)DAB (3,3‘-diaminobenzidine) is a widely used chromogen in immunohistochemical and immunoblotting applications.S-99014-103;S-99014-1030103ml;1030ml
Chromogens for HRPHRP-Green Solution Set (2 components)The HRP-Green Solution Set is a new chromogen used in immunohistochemical and chromogenic in situ hybridization applications.S-99056-103;S-99056-1030103ml;1030ml
Chromogens for HRPHRP-Green Solution Set (MxE)The HRP-Green Solution Set (MxE) is a unique chromogen used in immunohistochemical and chromogenic in situ hybridization applications that is mixable in equal parts.S-99070-100;S-99070-2000100ml;2000ml
Chromogens for HRPAP-Red Solution Set IHC (2 components)The AP-Red Solution Set IHC is a chromogen used in immunohistochemical applications.S-99065-103103ml
Chromogens for HRPAP-Red Solution Set ISH (2 components)The AP-Red Solution Set ISH is a chromogen used in chromogenic in situ hybridization applications.S-99061-10301030ml
Chromogens for HRPNBT/BCIP Solution (ready-to-use)The NBT/BCIP Solution is a chromogen used in immunohistochemical and chromogenic in situ hybridization applications.S-99064-500500ml
CounterstainsMayer`s Hematoxylin Solution (ready-to-use)Mayer’s Hematoxylin Solution is a staining reagent for histological applications.S-99025-10001000ml
CounterstainsNuclear Blue Solution (ready-to-use)Nuclear Blue Solution is a hematoxylin based reagent for counterstaining applications in in situ hybridization (ISH) and immunohistochemistry (IHC) procedures using common chromogens like AEC and DAB.S-99035-10001000ml
CounterstainsNuclear Fast Red Solution (ready-to-use)Nuclear Fast Red Solution is designed for use as a counterstaining solution in immunohistochemistry (IHC) procedures using common chromogens like BCIP/NBT.S-99031-10001000ml
CounterstainsNuclear Red Solution (ready-to-use)Nuclear Red Solution is a nuclear fast red (a.k.a. Kernechtrot) based reagent for counterstaining applications in in situ hybridization (ISH) and immunohistochemistry (IHC) procedures.S-99033-500;S-99033-1000500ml;1000ml
CounterstainsNuclear Green Solution (ready-to-use)Ready-to-use Nuclear Green Solution optimized for the use in immunohistochemical (IHC) and in situ hybrididzation (ISH) procedures. Suitable for aqueous and non- aqueous mountants.S-99104-10001000ml
Ancillary Reagents1% BSA Ab Diluent (ready-to-use)The 1% BSA Ab Diluent is a stabilizer and diluent for all antibodies routinely used in immunohistochemistry (IHC) and in situ hybridization (ISH) applications.S-99068-10001000ml
Ancillary Reagentsone4all-Antibody Stabilizer (ready-to-use)The one4all-Antibody Stabilizer is a unique stabilizer for all antibody-enzyme conjugates routinely used in immunohistochemistry (IHC) and in situ hybridization (ISH) applications as well as in ELISA.S-99030-10001000ml
Ancillary ReagentsPepsin Solution (ready-to-use)Pepsin is a commonly used digestive enzyme for immunohistochemical (IHC) and in situ hybridization (ISH) procedures.S-99003-50;S-99003-500;S-99003-100050ml;500ml;1000ml
Ancillary ReagentsPepsin Solution for Cytology (ready-to-use)Pepsin Solution for Cytology is a digestive enzyme solution used in in situ hybridization (ISH) procedures in cytology specimens.S-99053-500;S-99053-1000500ml;1000ml
Ancillary ReagentsProteinase K Solution (ready-to-use)The Proteinase K Solution is specifically designed for use in the pretreatment of formalin-fixed tissue for in situ-hybridization (ISH) procedures.S-99080-100100ml
Ancillary ReagentsDuraTect™ DAPI/Antifade Solution (ready-to-use)The DuraTect™ DAPI/Antifade Solution is a refrigerator-stable formula for preserving fluorescence.S-99081-10;S-99081-100;S-99081-50010ml;100ml;500ml
Ancillary ReagentsDuraTect™ DAPI/Antifade Solution "ultra" (ready-to-use)The DuraTect™ DAPI/Antifade Solution "ultra" is a refrigerator-stable formula for preserving fluorescence.S-99098-5050ml
Ancillary ReagentsCOT-DNA, human (10mg/ml)The COT fraction of human genomic DNA predominantly consists of rapidly annealing repetitive sequences.S-99040-1;S-99040-10;S-99040-501mg;10mg;50mg



" data-original="http://haemtech.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="艾美捷科技代理42 life sciences品牌全系列产品">
艾美捷科技代理42 life sciences品牌全系列产品
...
阅读详情
invivoCrown IV0102替换BioXCell BE0003-1 invivoCrown IV0102替换BioXCell BE0003-1
InVivoPro Anti-Mouse CD4 in vivo antibody, Clone GK1.5 ...
阅读详情

Copyright © 2026 Powered by haemtech中国区代理商/公司/官网   鄂ICP备10204150号-10 sitemap